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Selenium supplementation refers to the use of dietary supplements containing selenium, an essential trace mineral required for various physiological functions, including antioxidant defense, immune function, and thyroid hormone metabolism. Common supplemental forms include selenomethionine, selenium-enriched yeast, sodium selenite, and sodium selenate. Supplementation is typically recommended when dietary intake is insufficient or deficiency risk exists, but should be used within recommended limits due to potential toxicity risks at higher doses. Most individuals meet their needs through diet alone unless specific risk factors exist.
Selenium is incorporated into selenoproteins, which function as antioxidants, participate in thyroid hormone metabolism, and support immune function.
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