Target intelligence / Profile preview

Selenoprotein T pseudogene 1 (SELENOTP1)

Target
SELENOTP1
Molecular classification
Other, Pseudogene
01

Overview

Selenoprotein T pseudogene 1 (SELENOTP1) is a non-coding genetic locus annotated as a pseudogene related to the SELENOT gene, which encodes Selenoprotein T, an essential selenocysteine-containing oxidoreductase found in the endoplasmic reticulum[4][1]. SELENOTP1 does not encode a functional protein, and there is no evidence it plays a role as a therapeutic target, biomarker, or disease mediator[4]. Pseudogenes are often remnants of gene duplication or mutation and do not participate in standard biological molecular functions. If you are interested specifically in Selenoprotein T (SELENOT), it is an important oxidoreductase with roles in redox regulation, calcium mobilization, hormone synthesis, and neuroprotection, and has associated disease links (e.g., Keshan disease, congenital myopathy, Parkinson's disease risk)[1][6][4][2], but SELENOTP1 itself is not a drug target.

Other names
SELENOTP1
02

Mechanism of action

None (not a druggable target)

03

Biological functions

None (no protein product, no known biological function)
04

Disease associations

None directly
05

Safety considerations

None relevant
06

Interacting drugs

None
07

Biomarkers

None known

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