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Sensory processing modulation refers to the central nervous system’s process of regulating and filtering neural signals arising from various sensory modalities, determining the thresholds and responsiveness to sensory input, and influencing behavioral responses[5][2][4]. This process involves a balance between excitatory neurotransmission (primarily glutamate) and inhibitory neurotransmission (primarily GABA), and is often dysregulated in disorders such as sensory modulation disorder, autism, and certain pain syndromes[2][5]. Sensory processing modulation is achieved through distributed neural circuits, neurotransmitters, and synaptic mechanisms, but is not attributable to one single molecular entity or discrete druggable target[5][2][4].
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