Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Septin-11 (SEPTIN11)
- Target
- SEPTIN11
- Molecular classification
- Cytoskeletal GTPase, Filament-forming protein, Cytoskeleton component
01
Overview
Septin-11 is a cytoskeletal filament-forming GTPase with key regulatory roles in cell morphology, migration, and division, as well as synaptic architecture, with major implications in cancer metastasis and neuronal disorders[1][2][3][4].
- Other names
- SEPTIN11SEP11SEPT11FLJ10849Epididymis secretory sperm binding proteinSeptin-11septin-11
02
Biological functions
Cytoskeleton organization/reorganizationCell motilityCell migration/invasionCytokinesisVesicle traffickingDendritic arborizationDendritic spine formationPostsynaptic scaffoldingCell adhesion regulation
03
Disease associations
Cancer (hepatocellular carcinoma, differentiated thyroid cancer, acute lymphoblastic leukemia)Neurodegenerative disease/neuropathologyChronic neutrophilic leukemiaAmyotrophic neuralgia
04
Safety considerations
Tissue toxicity due to disruption of essential cytoskeletal and synaptic functionscomplexity due to alternative splicing and septin family redundancy
05
Biomarkers
High expression predicts poor prognosis in hepatocellular carcinomapotential metastasis/invasion marker in tumors
Beyond the preview
Go deeper on Septin-11 (SEPTIN11).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Septin-11 (SEPTIN11).