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Serine and arginine rich splicing factor 10 pseudogene 2 (SRSF10P2)

Target: SRSF10P2
Molecular classification: Other: Pseudogene (Processed pseudogene; non-coding RNA gene)

Overview

Serine and arginine rich splicing factor 10 pseudogene 2 (SRSF10P2) is a processed pseudogene located on human chromosome 20 (20p12.3). It is homologous to the functional gene SRSF10 which encodes a member of the SR protein family involved in RNA splicing, but SRSF10P2 does not encode a functional protein. SRSF10P2 has alternative names including FUSIP1P2 and SFRS13AP2. No evidence currently supports SRSF10P2 as a protein-coding gene, therapeutic target, receptor, or biomarker. Its biological role, if any, may include non-coding RNA functions such as regulation of parental gene expression through miRNA sponging or production of small regulatory RNAs, although this has not been specifically validated for SRSF10P2. Pseudogenes as a category are being studied for potential impacts on cancer and other diseases, but there are no data specifically supporting SRSF10P2 in these functions.

Other names: FUSIP1P2SFRS13AP2dJ836E8.1

Biological functions

Other: While most pseudogenes were considered nonfunctional, recent research suggests some may regulate gene expression, typically at the RNA level via mechanisms such as small RNA production or acting as competing endogenous RNAs (ceRNAs/sponges for microRNAs), but SRSF10P2 specifically has not been extensively studied for such functions

Disease associations

Other: There is no direct evidence linking SRSF10P2 to disease, though dysregulation of pseudogenes in general, or those related to splicing factors, may influence cancer or other pathologies; however, SRSF10P2 has not been specifically implicated

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