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Target intelligence / Profile preview
Serine protease 38 (PRSS38)
- Target
- PRSS38
- Molecular classification
- Enzyme, Serine-type endopeptidase, Protease
01
Overview
Serine protease 38 (PRSS38) is a member of the serine-type endopeptidase (protease) family, encoded by the PRSS38 gene in humans as well as orthologs in mouse (Prss38) and rat (Prss38). It is predicted to catalyze the hydrolysis of peptide bonds in a range of biological processes, including general proteolysis, by acting in the extracellular region. Its enzymatic function is based on a characteristic serine residue in the active site. The gene is expressed in multiple tissues and is under investigation for its expression in various cancer types, though its precise physiological and disease roles are still being determined. There are no known approved drugs or therapeutic agents targeting this molecule, and it has no established use as a biomarker as of current evidence.
- Other names
- PRSS38MPN2Marapsin-2marapsin 2protease, serine 38serine protease MPN2serine protease 38, MPN2
02
Mechanism of action
Null
03
Biological functions
Proteolysis (protein degradation)Serine-type endopeptidase (hydrolysis of peptide bonds)Potential roles in development and differentiation (from mouse model annotations)
04
Disease associations
Potential involvement in cancer (studied in several cancer types for expression and survival correlation; role remains to be fully characterized)Other (insufficient data for precise disease mechanism, but expressed in multiple tissues and cancer contexts)
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