Serine-rich and transmembrane domain-containing protein 1 (SERTM1)

Serine-rich and transmembrane domain-containing protein 1 (SERTM1, encoded by the SERTM1 gene, also known as C13orf36) is a putative membrane protein in humans, predicted to be rich in serine residues and to possess transmembrane regions[3][8][9]. Human SERTM1 is classified as a protein-coding gene (Gene ID: 400120, Chromosome 13)[3][8]. Its protein product’s function is not experimentally validated, but it is predicted to localize to cellular membranes[3][9]. SERTM1 is expressed in multiple human tissues, including the brain, but no tissue-specific functional role or linkage to specific physiological or pathophysiological processes has been established[5][6]. There are no reports of SERTM1 as a drug target, disease biomarker, or involvement in signaling pathways, enzyme functions, transport activity, or receptor-like activity based on current genomic and proteomic database annotations[3][8][9]. The gene is sometimes listed as C13orf36 in older literature, reflecting its chromosomal location before formal naming[3]. SERTM1 has been used in transcriptomic profiling as a molecular marker in certain neuronal subtypes (e.g., mitral cell subtypes of the mouse olfactory bulb), but no direct functional role has been assigned[2]. No mechanisms of action, interacting drugs, disease roles, or safety profile are available for this protein at this time.

Other names

SERTM1C13orf36Serine-rich and transmembrane domain-containing protein 1