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Serotonin Modulator

Molecular classification
Drug Class, Pharmacological Agent
01

Overview

A serotonin modulator is a type of drug that acts on the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter system in the brain. These agents have a multimodal mechanism of action: they both modulate one or more subtypes of serotonin receptors and inhibit the reuptake of serotonin, thereby increasing its synaptic concentration. This dual action distinguishes them from selective serotonin reuptake inhibitors (SSRIs), which primarily block reuptake without significant direct receptor modulation.

Other names
5-HT ModulatorSerotonergic Modulator
02

Mechanism of action

Modulates multiple post-synaptic/pre-synaptic serotonin receptors; inhibits SERT

03

Biological functions

Neurotransmission modulationMood regulationAnxiolytic effects
04

Disease associations

Major Depressive DisorderAnxiety Disorders
05

Interacting drugs

Vortioxetine

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