Serpin family A member 7 pseudogene 1 (SERPINA7P1)

SERPINA7P1 is classified as a polymorphic pseudogene within the serpin superfamily, specifically corresponding to the clade A (alpha-antiproteinase-like) group[3][5][8]. Unlike functional serpins, pseudogenes do not encode proteins due to genetic disruptions or mutations that prevent translation[3][5]. SERPINA7P1’s sequence is related to the functional gene SERPINA7 (thyroxine-binding globulin), which is a transporter protein; however, SERPINA7P1 itself does not function in thyroid hormone transport or protease inhibition[5][2][8]. It has no documented biological role, protein product, or significance as a therapeutic or diagnostic marker. Most available information notes that this pseudogene occurs in the human genome as a non-coding, non-functional allele in some populations[3][8]. There is no evidence of SERPINA7P1 being a therapeutic target, biomarker, or having clinical relevance[3][5][8].

Other names

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 pseudogene 1SERPINA7P1