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Target intelligence / Profile preview
Serpin family B member 9 pseudogene 1 (SERPINB9P1)
- Target
- SERPINB9P1
- Molecular classification
- Pseudogene, Serpin superfamily (by sequence), Other (not a receptor, enzyme, transporter, or functional molecule)
01
Overview
Serpin family B member 9 pseudogene 1 (SERPINB9P1) is a non-protein-coding genomic sequence homologous to the functional SERPINB9 gene, which belongs to the serpin superfamily of protease inhibitors[1][3][5][7]. As a pseudogene, SERPINB9P1 does not produce a protein and has no known biological activity or role in disease or therapy. It is listed in human gene databases with the alias MGC39372, located on chromosome 6[1][3][7]. The functional protein Serpin family B member 9 (SERPINB9), also known as PI-9, is an intracellular serine protease inhibitor with established roles in immune regulation and cancer via inhibition of granzyme B[4][6]. This is a distinct entity from the SERPINB9P1 pseudogene, which is not a therapeutic target and has no protein product[1][3][5][7].
- Other names
- MGC39372serpin peptidase inhibitor, clade B (ovalbumin), member 9, pseudogene 1
02
Mechanism of action
None (no mechanism applicable)
03
Biological functions
None (no evidence of protein or functional product; canonical function not observed for pseudogenes)
04
Disease associations
None (there is no evidence linking this pseudogene to any diseases; functional SERPINB9—not the pseudogene—is involved in immune response and cancer, but not SERPINB9P1)
05
Safety considerations
None (no therapeutic interventions established)
06
Interacting drugs
None (as a pseudogene, it does not produce a protein for drugs to bind or inhibit)
07
Biomarkers
None (no evidence supporting use as a clinical biomarker)
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