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SET pseudogene 22 (SETP22) is a non-functional genomic locus similar in sequence to the active SET nuclear proto-oncogene, but lacking the ability to produce a functional protein[1][2]. Pseudogenes such as SETP22 arise by mutation or genome rearrangement of an ancestral gene and typically accumulate changes that disable protein-coding capacity[6][12]. While some pseudogenes are transcribed and may regulate their parent genes or function as non-coding RNAs, there is currently no evidence that SETP22 possesses biological activity or disease association[1][2][5]. Consequently, SETP22 is not considered a therapeutic target or biomarker. If you need information about the functional protein "SET nuclear proto-oncogene" (abbreviated as SET), which has established cellular roles and is discussed as a therapeutic target, let me know.
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