Target intelligence / Profile preview

SET pseudogene 22 (SETP22)

Target
SETP22
Molecular classification
Other (Pseudogene)
01

Overview

SET pseudogene 22 (SETP22) is a non-functional genomic locus similar in sequence to the active SET nuclear proto-oncogene, but lacking the ability to produce a functional protein[1][2]. Pseudogenes such as SETP22 arise by mutation or genome rearrangement of an ancestral gene and typically accumulate changes that disable protein-coding capacity[6][12]. While some pseudogenes are transcribed and may regulate their parent genes or function as non-coding RNAs, there is currently no evidence that SETP22 possesses biological activity or disease association[1][2][5]. Consequently, SETP22 is not considered a therapeutic target or biomarker. If you need information about the functional protein "SET nuclear proto-oncogene" (abbreviated as SET), which has established cellular roles and is discussed as a therapeutic target, let me know.

Other names
SETP22
02

Mechanism of action

None

03

Biological functions

None established for this pseudogeneSome pseudogenes can participate in gene regulation by acting as competing endogenous RNAs or influencing microRNA activity, but there is no specific evidence for SETP22
04

Disease associations

None establishedPseudogenes, including those related to SET, have been implicated in some regulatory contexts, cancer, and gene network modulation; however, this is not specifically established for SETP22
05

Safety considerations

None
06

Interacting drugs

None
07

Biomarkers

None

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