SET pseudogene 3 (SETP3)

SET pseudogene 3 (SETP3) is a processed pseudogene, meaning it is a DNA sequence derived from a functional ancestral gene (likely related to the SET gene) that has lost its protein-coding ability due to disabling mutations or lack of core promoters[1][2][4][5]. Pseudogenes like SETP3 are generally considered nonfunctional remnants; while some pseudogenes have been shown to play regulatory roles in gene expression at the level of RNA, there is no evidence that SETP3 does so[2][3][4]. Pseudogenes can complicate molecular genetic studies due to their sequence similarity to functional genes, but they are not direct therapeutic targets[4]. There are no known drugs, clinical biomarkers, safety concerns, or validated disease associations tied to SETP3. In summary, SET pseudogene 3 (SETP3) is not a valid therapeutic or biological target and should be excluded from most target-based analyses[1][2][4].

Other names

SETP13