Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
SFT2 domain-containing protein 2 (SFT2D2)
- Target
- SFT2D2
- Molecular classification
- Other
01
Overview
SFT2 domain-containing protein 2 (SFT2D2) is a predicted multipass membrane protein involved in vesicle-mediated transport and protein trafficking, particularly in endosome-to-Golgi retrieval. It is widely expressed in the brain and immune cells, with high abundance in plasmacytoid dendritic cells and microglia. Elevated expression and autoantibody response to SFT2D2 have been linked to schizophrenia and potentially neurodegenerative and autoimmune disorders, though its role as a therapeutic target or in drug interactions remains uncharacterized.
- Other names
- Vesicle transport protein SFT2BUNQ512/PRO1027UNQ512dJ747L4.C1.2SFT2 domain-containing protein 2SFT2B
02
Biological functions
Protein transportVesicle-mediated transportEndosome-to-Golgi retrieval
03
Disease associations
Neurodegenerative diseaseSchizophreniaAutoimmunity
04
Biomarkers
Anti-SFT2D2 IgG (in schizophrenia)
Beyond the preview
Go deeper on SFT2 domain-containing protein 2 (SFT2D2).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on SFT2 domain-containing protein 2 (SFT2D2).