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SFTPD antisense RNA 1 (SFTPD-AS1) is annotated as a long non-coding RNA transcribed from the locus opposite the SFTPD protein-coding gene, which encodes surfactant protein D. Antisense RNAs typically function in regulating expression of their sense gene through RNA-RNA interactions, epigenetic modification, or chromatin remodeling, but there is currently no specific published data describing the biological function, expression pattern, disease relevance, or clinical utility of SFTPD-AS1. Canonical knowledge and public databases recognize the existence of this transcript, but its precise molecular and clinical role is not established, and it is not considered a drug target or established biomarker at this time.
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