Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
SGMS1 antisense RNA 1 (SGMS1-AS1)
- Target
- SGMS1-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Other
01
Overview
SGMS1 antisense RNA 1 (SGMS1-AS1) is a long non-coding RNA gene transcribed antisense to the SGMS1 gene locus. It is predicted to act upstream of or within the positive regulation of myelination and control of gene expression[5]. Recent research implicates SGMS1-AS1 in cancer biology, including a role in the regulation of metabolic pathways in colon cancer through ceRNA mechanisms involving microRNA and CPT2, suggesting it may participate in tumor metabolism or progression as part of a regulatory axis[6]. Its functional characterization and disease relevance are areas of ongoing study. Note: SGMS1-AS1 should not be confused with SGMS1, which encodes the enzyme sphingomyelin synthase 1, a bona fide protein and therapeutic target in cancer and metabolic diseases[1][2][3]. Current evidence does not support classifying the antisense RNA SGMS1-AS1 itself as a direct drug target.
- Other names
- SGMS1 antisense RNA 1SGMS1-AS1
02
Mechanism of action
Not applicable. No drugs are reported to target SGMS1-AS1 directly.
03
Biological functions
Regulation of gene expressionPredicted positive regulation of myelinationModulation of other gene regulatory pathwaysPossibly involved in metabolic reprogramming in cancer
04
Disease associations
Cancer (evidence for a functional role in colon cancer)Other (potential, based on emerging research; direct links to other diseases currently limited)
Beyond the preview
Go deeper on SGMS1 antisense RNA 1 (SGMS1-AS1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on SGMS1 antisense RNA 1 (SGMS1-AS1).