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SH3 domain-binding glutamic acid-rich protein like 3 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

This gene ("ENSG00000270382") represents a **pseudogene** related to *SH3 domain-binding glutamic acid-rich protein like 3*, meaning it shares significant sequence homology to the functional SH3BGRL3 gene but is not predicted to encode a functional protein[2][4]. Pseudogenes arise via duplication or retrotransposition and often contain sequence disruptions such as frameshifts or premature stop codons[2][4]. In rare cases, pseudogenes are capable of producing functional non-coding RNAs, including those that can act as microRNA decoys, small interfering RNAs, or regulatory elements for other genes, but there is no evidence that this pseudogene has such activity[2][4]. It is not considered a therapeutic target and is not associated with interacting drugs, mechanisms of action, or biomarkers. Pseudogenes can introduce confusion in genome annotation and may sometimes be misclassified in sequence databases[2]. This entry is a pseudogene, not a functional target, receptor, enzyme, or therapeutic entity; there is no protein product nor known physiological function, thus it should not be considered a valid therapeutic target[2][4]. If you are seeking information on a functional, protein-coding target, refer instead to SH3BGRL3 (SH3 domain-binding glutamic acid-rich-like protein 3), which is the bona fide gene and protein[1].

Other names
SH3BGRL3 pseudogeneSH3 domain binding glutamic acid-rich protein-like 3 pseudogene
02

Biological functions

Other (no known direct biological function, but may have regulatory RNAs or serve as miRNA decoy[2][4])
03

Disease associations

Other (potential non-coding regulatory effects possible, but not established as a disease gene or therapeutic target[2][4])

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