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Target intelligence / Profile preview
SH3 domain binding kinase family member 3 (SBK3)
- Target
- SBK3
- Molecular classification
- Enzyme, Serine/threonine-protein kinase
01
Overview
SH3 domain binding kinase family member 3 (SBK3) is a protein-coding gene predicted to encode a serine/threonine-protein kinase with putative roles in chromatin remodeling and protein phosphorylation[2][3]. Experimental evidence indicates that SBK3 suppresses angiotensin II-induced cardiac hypertrophy, suggesting involvement in cardiovascular disease modulation[4]. Functional associations and gene ontology annotations support its classification as a kinase, but the full biological and pharmacological significance remains under investigation[2][3].
- Other names
- uncharacterized serine/threonine-protein kinase SBK3SGK110SgK110SH3 domain-binding kinase family member 3Sugen kinase 110putative serine/threonine-protein kinase SBK3SH3-binding domain kinase family member 3
02
Biological functions
Protein serine/threonine kinase activityChromatin remodeling
03
Disease associations
Cardiovascular disease (cardiac hypertrophy)
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