SHC (Src homology 2 domain containing) transforming protein 1 pseudogene

The SHC (Src homology 2 domain containing) transforming protein 1 pseudogene refers to a genomic DNA sequence in humans that closely resembles the SHC1 gene, which encodes a protein involved in signal transduction by acting as an adaptor in receptor tyrosine kinase pathways[1][4]. However, as a pseudogene, it does not encode a functional protein product because of disabling mutations that prevent transcription or translation[2][5]. Pseudogenes are generally considered non-functional remnants of genes; some can have a regulatory role, but most lack any direct protein-coding or canonical molecular activity[2][5]. SHC1 and related SHC proteins play critical roles in cell signaling, particularly in pathways mediated by receptor tyrosine kinases, but the SHC1 pseudogene itself is not a therapeutic or biological target and does not produce a functional SHC protein[1][2][4][5]. The gene identifier ENSG00000283269 refers to a pseudogene, and not to any functional gene or protein.

Other names

SHC1 pseudogeneSHC pseudogeneSHC1PSHC transforming protein 1 pseudogene