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"Shigella cell surface receptors" is not a recognized molecular entity, protein, or receptor, but rather a collective term for the various host cell surface structures and molecules that Shigella bacteria utilize to adhere to, invade, and manipulate host cells. Shigella pathogenesis involves a type III secretion system (T3SS), which allows delivery of bacterial effector proteins that modulate host cell actin cytoskeleton and signaling[1][3][4]. Rather than binding a specific host receptor, Shigella uses surface proteins like IcsA and effectors such as IpaB, IpaC, and others to induce membrane ruffling and invasion. Some effector-host interactions involve host GTPases (Rho, Rac, Cdc42) and cytoskeletal elements, but there is no single "Shigella cell surface receptor" as a discrete, druggable target[1][3][4][2]. Therefore, the entry "Shigella cell surface receptors" is too vague, does not correspond to a specific molecule, and is not itself a therapeutic target. If your intention is to reference a specific mechanism (e.g., T3SS interaction with host membranes or host protein N-WASP targeted by IcsA), more specificity or a molecular name/abbreviation is required.
Not applicable for "Shigella cell surface receptors" as a discrete target
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