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This entry (ENSG00000274541) refers to a pseudogene related to the Siah E3 ubiquitin protein ligase family member 3 (SIAH3). Pseudogenes are DNA sequences that resemble known genes but are generally non-functional due to mutations, deletions, or truncations, and do not encode active proteins. The functional version, SIAH3 (canonical gene: ENSG00000215475), is a protein-coding gene encoding an E3 ubiquitin ligase involved in protein stability and negative regulation of protein targeting to mitochondria. The pseudogene does not participate in these biological processes and is not considered a molecular target in the context of receptor, enzyme, or transporter function[3].
Not applicable.
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