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Sialoglycan

Molecular classification: Glycan, Carbohydrate

Overview

Sialoglycans are glycans (complex carbohydrates) that terminate with one or more sialic acid residues. These structures are abundantly displayed on the surface of vertebrate cells and in secreted molecules, where they play critical roles in cell-cell communication, immune modulation, and pathogen recognition. The diversity of sialoglycans arises from variations in the type of sialic acid, their chemical modifications, and the specific linkages to underlying sugar chains.

Other names: Sialylated glycansSialic acid-containing glycansSialylated oligosaccharides

Biological functions

Cell signaling modulationImmune system regulationPathogen interactionCell-cell communicationModulating cell adhesion

Disease associations

CancerAutoimmune disordersInfection

Biomarkers

Tumor-associated carbohydrate antigens

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