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Target intelligence / Profile preview
Sialic Acid Receptor (SA Receptor)
- Target
- SA Receptor
- Molecular classification
- Carbohydrate Receptor, Glycoprotein, Glycolipid, Lectins
01
Overview
Sialic acid receptors are carbohydrate structures, primarily terminal residues on glycoproteins and glycolipids, that serve as crucial binding sites for various biological processes, including cell-cell interactions, immune modulation, and pathogen entry. They are key receptors for viruses like influenza, and their overexpression is implicated in cancer metastasis.
- Other names
- Sialoglycan ReceptorSialic acid-binding receptorNeu5Ac ReceptorN-acetylneuraminic acid ReceptorSialoglycoconjugate Receptor
02
Mechanism of action
Inhibition of viral entry/release by blocking sialic acid binding or cleaving sialic acids
03
Biological functions
Cell adhesionCell signalingImmune modulationPathogen recognitionHydration maintenanceSynaptic function
04
Disease associations
InfectionCancer metastasisAutoimmunityInfluenzaNeurological disorders
05
Safety considerations
Off-target effects of sialidase inhibitorsImmune evasion mechanismsPotential for altered cellular interactions
06
Interacting drugs
Oseltamivir
2 more in the full profile.
07
Biomarkers
Sialic acid expression levels in cancer cellsSiglec expression levelsGlycan profiles
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