Signal peptidase complex catalytic subunit SEC11B (SEC11B)

SEC11B is a putative catalytic subunit of the signal peptidase complex, an essential multi-protein assembly in eukaryotes that removes signal peptides from nascent secretory and membrane proteins as they enter the lumen of the endoplasmic reticulum[3][5][6][9]. The complex is crucial for the maturation and proper functioning of many proteins. SEC11B, as a member of the serine protease family, is predicted to harbor catalytic activity, although its functional characterization in humans is limited and it remains less well-studied compared to the main SEC11A subunit. There are no established disease associations, drug interactions, or therapeutic implications registered for SEC11B at present[3][5][9]. Its essential function in archaea and possible redundancy in higher eukaryotes suggest a conserved biological role in protein maturation[1].

Other names

SEC11BPutative signal peptidase complex catalytic subunit SEC11BSEC11L2SPCS4BSEC11-like protein 2