Target intelligence / Profile preview

Signal peptidase complex subunit 3 homolog pseudogene (SPCS3 pseudogene)

Target
SPCS3 pseudogene
Molecular classification
Other (pseudogene, not a functional class such as enzyme, receptor, etc.)
01

Overview

The "signal peptidase complex subunit 3 homolog pseudogene" (ENSG00000275406) is a non-protein-coding sequence related to the SPCS3 gene. Pseudogenes are remnants of functional genes that have lost their protein-coding ability and generally do not participate directly in biological processes. The functional counterpart, SPCS3 (Signal Peptidase Complex Subunit 3), is an essential protein-coding gene that encodes a component of the signal peptidase complex, which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the endoplasmic reticulum, with roles in viral protein maturation and disease. However, these biological functions and disease associations do not apply to the pseudogene itself.

Other names
SPCS3 pseudogeneSignal peptidase complex subunit 3 pseudogeneENSG00000275406
02

Mechanism of action

None for the pseudogene.

03

Biological functions

None. Pseudogenes generally lack biological function unless there is evidence for regulatory RNA roles; no such evidence is provided for this pseudogene
04

Disease associations

None. Disease associations listed for SPCS3 (protein-coding) gene (e.g., mixed ductal-endocrine carcinoma, Omsk hemorrhagic fever) do not apply to the pseudogene
05

Safety considerations

None reported
06

Interacting drugs

None. There are no known drugs interacting with this pseudogene; if a drug targets the signal peptidase complex, it will interact with components encoded by protein-coding genes like SPCS3
07

Biomarkers

None

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