Signal recognition particle 14kDa pseudogene

Signal recognition particle 14kDa pseudogene (ENSG00000271330) is a genomic sequence that closely resembles the gene encoding the 14kDa protein subunit of the signal recognition particle, but due to mutations or deletions, it does not produce a functional protein[4][6]. Pseudogenes like this typically arise from gene duplication or retrotransposition, followed by disabling mutations[2][6]. While most pseudogenes are considered nonfunctional "genomic fossils," they can sometimes be transcribed into RNA with possible, though rare, regulatory roles[8]. This pseudogene should not be confused with functional members of the signal recognition particle complex, which plays a central role in co-translational targeting of secretory and membrane proteins to the endoplasmic reticulum[1][3][5][7]. As a pseudogene, ENSG00000271330 is not a therapeutic target, does not code for a functional protein, and has no established direct role in disease or drug interaction.