Target intelligence / Profile preview

Silicon Dioxide (SiO₂)

Target: SiO₂
Molecular classification: Inorganic compound, Abrasive

Overview

Silicon dioxide (SiO₂), often in the form of amorphous silica, is a widely used abrasive agent in oral care products for the mechanical removal of dental plaque biofilm. It functions by physically disrupting and detaching plaque from tooth surfaces during brushing or professional cleaning. Its efficacy depends on particle size, shape, hardness, and concentration. While effective, safety considerations focus on minimizing enamel abrasion through careful control of particle characteristics.

Other names: SilicaAmorphous Silica

Mechanism of action

Mechanical abrasion and removal of dental plaque biofilm

Biological functions

Mechanical plaque removal

Disease associations

Dental cariesPeriodontal disease

Safety considerations

Enamel abrasion (if particle size/concentration is not properly controlled)

Beyond the preview

Go deeper on Silicon Dioxide (SiO₂).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Silicon Dioxide (SiO₂).

Explore the full profile