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Target intelligence / Profile preview
Silver Nanoparticles (AgNPs)
- Target
- AgNPs
- Molecular classification
- Nanomaterial, Inorganic compound
01
Overview
Silver nanoparticles (AgNPs) are nanoscale particles of silver that exhibit anti-inflammatory, antimicrobial, and antioxidant properties. They modulate cytokine production, inhibit COX-2, disrupt bacterial metabolism, and scavenge free radicals. AgNPs are being investigated for wound healing, burn treatment, and other pharmaceutical applications.
- Other names
- Silver particlesNano silverColloidal silver
02
Mechanism of action
Silver nanoparticles exert anti-inflammatory effects by reducing pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), increasing anti-inflammatory cytokines, inhibiting COX-2 and MMP-3 expressions, affecting bacterial cellular metabolism, and eliminating free radicals.
03
Biological functions
Antimicrobial activityAnti-inflammatory activityAntioxidant activityCytokine modulationEnzyme inhibition
04
Disease associations
InflammationInfectionWound healingBurns
05
Safety considerations
Potential toxicity depending on particle size, shape, surface coating, concentration, exposure duration, and route of administrationEnvironmental impact
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