Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Sinapis alba extract, commonly known as white mustard extract, is a complex phytochemical mixture derived from the seeds of the Sinapis alba plant rather than a singular therapeutic target molecule. Its primary bioactive profile includes the glucosinolate sinalbin, which undergoes enzymatic conversion by myrosinase into p-hydroxybenzyl isothiocyanate when exposed to moisture [1][2]. Traditionally, this extract is utilized in topical applications as a rubefacient and counter-irritant to alleviate muscular pain and respiratory congestion by inducing localized vasodilation [3][4]. At a molecular level, its components have been investigated for their ability to exert antimicrobial and antioxidant effects, potentially through the modulation of oxidative stress response elements like Nrf2 [1][5]. Because it is a crude botanical extract containing multiple chemical species, it does not possess a canonical protein target and is instead characterized by its broad multi-target pharmacological activity [2][3].
Exerts therapeutic effects primarily through its bioactive glucosinolate, sinalbin, which is hydrolyzed by the endogenous enzyme myrosinase into p-hydroxybenzyl isothiocyanate; this compound acts as a local irritant (rubefacient) to stimulate blood flow and may modulate Nrf2 and inflammatory cytokine pathways.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Explore the programs pursuing this target and their development progress.
Follow the clinical studies evaluating therapies directed at this target.
Compare approaches across drug candidates, modalities, and indications.
Investigate the research and source evidence behind target biology and development.
Explore patent activity around therapies and technologies addressing this target.
Connect target biology, drug development, and emerging evidence in your research.
See how Gosset can support your research on Sinapis alba extract.