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Single-pass membrane and coiled-coil domain-containing protein 2 (SMCO2) is a protein encoded by the human SMCO2 gene (also known as C12orf70 or LOC341346)[5][8][9][11]. It is structurally characterized by the presence of a single transmembrane domain and coiled-coil motifs, suggesting a potential role in membrane-associated structural or scaffolding functions. However, its specific biological function, interacting partners, associated signaling pathways, and involvement in disease remain *uncharacterized* according to current genomic and proteomic annotations. The gene is broadly conserved and expressed but has not been implicated in therapeutic targeting, pathological mechanisms, or biomarker applications[5][9][11].
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