SKAP1 antisense RNA 1 (SKAP1-AS1)

**SKAP1 antisense RNA 1 (SKAP1-AS1)**, also known as **RP11-456D7.1**, is a long non-coding RNA transcribed from the antisense strand of the SKAP1 locus[3][4]. As a natural antisense transcript (NAT), it is classified as a non-coding RNA and is not translated into protein[6]. The general role of antisense RNAs, including lncRNAs like SKAP1-AS1, is to regulate gene expression through mechanisms such as transcriptional interference, modulation of chromatin structure, or RNA-RNA interactions. These actions may impact the expression of the sense gene (SKAP1) or other regulatory processes[2][6]. There is no published evidence that SKAP1-AS1 functions as a therapeutic target, nor is there information on clinical drugs or biomarker use specific to this RNA. The broader class of antisense RNAs is under investigation for roles in disease, but no direct association with specific diseases or therapeutic interventions is currently documented for SKAP1-AS1.

Other names

RP11-456D7.1