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Skeletal muscle group

Molecular classification
Other
01

Overview

Skeletal muscle is a type of striated muscle tissue under voluntary control, responsible for movement, posture regulation, and heat production in vertebrates. Composed of multinucleated fibers (myocytes), it includes various proteins such as actin, myosin, titin, and regulatory molecules that mediate contraction and relaxation cycles. Each skeletal muscle is organized in bundles (fascicles) surrounded by connective tissue and is innervated at the neuromuscular junction, where neuronal signals regulate contraction via acetylcholine release. Skeletal muscle is subject to a wide variety of diseases and adaptive processes but is not a molecular target itself for drug action[1][2][4]. The term "Skeletal muscle group" does not refer to a specific molecular target such as a receptor, enzyme, or protein. It is a general anatomical term describing a collection of skeletal muscles that perform related movements, rather than a distinct molecular entity that could serve as a drug target. In pharmacology and drug development, targets are nearly always specific proteins, receptors, enzymes, ion channels, or transporters—never a whole muscle or group of muscles. If you require molecular targets involved in skeletal muscle function (e.g., acetylcholine receptor, ryanodine receptor), please specify the molecule.

Other names
Skeletal muscle tissueStriated muscleVoluntary muscleMuscle fibers
02

Biological functions

MovementPosture maintenanceThermogenesisJoint stabilizationEndocrine function
03

Disease associations

Muscular dystrophyMyopathiesCachexiaSarcopeniaMuscle atrophyOther musculoskeletal diseases
04

Biomarkers

Creatine kinaseMyoglobinTroponinDystrophin

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