SKI-interacting protein pseudogene

The SKI-interacting protein pseudogene (ENSG00000235400, LOC652549) is a genomic sequence similar to the functional SKI-interacting protein gene (often abbreviated as SKIP or SNW1) but is classified as a pseudogene. Pseudogenes can arise from duplication or retrotransposition events and generally do not encode functional proteins due to accumulated mutations or lack of transcription[1]. The SKI-interacting protein itself is a well-studied coactivator and corepressor, regulating transcription and interacting with nuclear receptors and other transcriptional machinery[3][5]. However, this pseudogene form does not have a defined biological activity or role as a drug target, and its mention may be due to annotation artifacts or misidentification, not to genuine therapeutic interest.

Other names

LOC652549SKI-Interacting Protein (SNW1) PseudogeneENSG00000235400