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Skin Hydration (N/A)
- Target
- N/A
- Molecular classification
- Complex Biological Process, Physiological Process
01
Overview
Skin hydration refers to the water content within the skin, particularly the stratum corneum (SC). It is crucial for maintaining skin barrier function, elasticity, and overall health. This process involves a complex interplay of components such as Natural Moisturizing Factor (NMF), stratum corneum lipids, glycerol, hyaluronic acid, and aquaporin-3, which regulate water retention and prevent excessive transepidermal water loss (TEWL).
- Other names
- Cutaneous hydrationEpidermal hydrationStratum corneum hydration
02
Mechanism of action
N/A
03
Biological functions
Barrier functionWater retentionMaintenance of skin elasticityDesquamationRegulation of TEWL
04
Disease associations
XerosisEczemaPsoriasisAgeingDermatitis
05
Safety considerations
Irritation from occlusive agentsAllergic reactions to emollientsPotential for over-hydration (maceration)Impact of environmental factors (humidity, temperature)
06
Interacting drugs
Petrolatum
6 more in the full profile.
07
Biomarkers
TEWL (Transepidermal Water Loss)Corneometry (measurement of stratum corneum hydration)NMF (Natural Moisturizing Factor) levelsLipid composition of stratum corneum
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