SLC17A6 divergent transcript (SLC17A6-DT)

SLC17A6-DT (SLC17A6 divergent transcript) is a long non-coding RNA transcribed from a locus adjacent to the SLC17A6 gene, which encodes vesicular glutamate transporter 2. Divergent lncRNAs are a subclass of long non-coding RNAs that arise by transcription from promoters near protein-coding genes, often in an antisense or bidirectional manner. These lncRNAs can regulate the expression of nearby genes through chromatin remodeling, transcriptional interference, or recruitment of epigenetic regulators, as demonstrated by molecular analogs like GATA3-AS1[2]. However, SLC17A6-DT itself does not have experimentally validated biological function, targetability, or disease relevance. The existence, sequence, and regulatory impact of SLC17A6-DT as a distinct entity remain putative, requiring further validation. It is not recognized as a therapeutic target, receptor, enzyme, or transporter[2].

Other names

lncRNA-GluGlutamate signaling associated lncRNASLC17A6-DTSLC17A6 divergent transcriptglutamate signaling associated lncRNA