Target intelligence / Profile preview

SLC25A51 pseudogene 3 (SLC25A51P3)

Target
SLC25A51P3
Molecular classification
Other (Pseudogene; not an active protein-coding transporter)
01

Overview

SLC25A51 pseudogene 3 (SLC25A51P3) is a pseudogene related to the SLC25A51 gene, which encodes a mitochondrial NAD⁺ transporter protein[1][2][3][4]. Pseudogenes like SLC25A51P3 are DNA segments derived from functional genes but contain disrupting mutations or deletions that prevent them from producing a functional protein. There is no evidence that SLC25A51P3 encodes an active protein product, mediates NAD⁺ transport, or plays any direct molecular or therapeutic role. It is not considered a drug target or relevant for biomarker development or disease association. The canonical target, SLC25A51 (not the pseudogene), is a mitochondrial inner membrane transporter responsible for importing NAD⁺ into the mitochondria and is an emerging therapeutic target in cancer metabolism and ageing research[2][3][4]. SLC25A51P3 exists as a non-coding, non-functional genomic locus and should not be confused with the functional SLC25A51 gene product. No aliases or alternative names are commonly used for SLC25A51P3 in scientific literature or major gene/protein databases. SLC25A51P3 appears to be a pseudogene, not an active transporter or receptor; it is not a therapeutic target and should not be used as a canonical entry for drug or biomarker discovery. The correct active molecule is "Solute carrier family 25 member 51" (SLC25A51).

02

Biological functions

None (pseudogenes typically lack biological function, though some may have regulatory roles in rare cases)
03

Disease associations

None established

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