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SLC25A51 pseudogene 3 (SLC25A51P3) is a pseudogene related to the SLC25A51 gene, which encodes a mitochondrial NAD⁺ transporter protein[1][2][3][4]. Pseudogenes like SLC25A51P3 are DNA segments derived from functional genes but contain disrupting mutations or deletions that prevent them from producing a functional protein. There is no evidence that SLC25A51P3 encodes an active protein product, mediates NAD⁺ transport, or plays any direct molecular or therapeutic role. It is not considered a drug target or relevant for biomarker development or disease association. The canonical target, SLC25A51 (not the pseudogene), is a mitochondrial inner membrane transporter responsible for importing NAD⁺ into the mitochondria and is an emerging therapeutic target in cancer metabolism and ageing research[2][3][4]. SLC25A51P3 exists as a non-coding, non-functional genomic locus and should not be confused with the functional SLC25A51 gene product. No aliases or alternative names are commonly used for SLC25A51P3 in scientific literature or major gene/protein databases. SLC25A51P3 appears to be a pseudogene, not an active transporter or receptor; it is not a therapeutic target and should not be used as a canonical entry for drug or biomarker discovery. The correct active molecule is "Solute carrier family 25 member 51" (SLC25A51).
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