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SLC7A14 antisense RNA 1 (SLC7A14-AS1) is a long non-coding RNA gene located adjacent to or overlapping with the SLC7A14 locus. As an antisense transcript, its sequence is complementary to the sense (protein-coding) transcript SLC7A14, which encodes a lysosomal cationic amino acid transporter involved in sensory cell maintenance[1][3][4][5]. Antisense RNAs like SLC7A14-AS1 are known to regulate gene expression at multiple levels — including transcription, RNA stability, and translation — often exerting effects in cis on their sense gene partners[2]. There is no direct evidence in the current scientific literature that SLC7A14-AS1 alone is implicated in disease, acts as a therapeutic target, or serves as a clinical biomarker. Summary of limitations: The primary literature discusses SLC7A14’s relevance as a gene and protein, but there is minimal information about the specific functions or disease associations of SLC7A14-AS1[1][4][5]. SLC7A14-AS1 is distinguished as an antisense RNA and not as a druggable target or receptor.
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