Target intelligence / Profile preview

SLC7A14 antisense RNA 1 (SLC7A14-AS1)

Target
SLC7A14-AS1
Molecular classification
Long non-coding RNA, Antisense RNA, Other (non-coding RNA)
01

Overview

SLC7A14 antisense RNA 1 (SLC7A14-AS1) is a long non-coding RNA gene located adjacent to or overlapping with the SLC7A14 locus. As an antisense transcript, its sequence is complementary to the sense (protein-coding) transcript SLC7A14, which encodes a lysosomal cationic amino acid transporter involved in sensory cell maintenance[1][3][4][5]. Antisense RNAs like SLC7A14-AS1 are known to regulate gene expression at multiple levels — including transcription, RNA stability, and translation — often exerting effects in cis on their sense gene partners[2]. There is no direct evidence in the current scientific literature that SLC7A14-AS1 alone is implicated in disease, acts as a therapeutic target, or serves as a clinical biomarker. Summary of limitations: The primary literature discusses SLC7A14’s relevance as a gene and protein, but there is minimal information about the specific functions or disease associations of SLC7A14-AS1[1][4][5]. SLC7A14-AS1 is distinguished as an antisense RNA and not as a druggable target or receptor.

Other names
SLC7A14-AS1SLC7A14 antisense RNA 1
02

Biological functions

Regulation of gene expression (through antisense mechanisms)
03

Disease associations

Other (Potential regulatory role inferred due to genomic linkage to SLC7A14, which itself is linked to retinitis pigmentosa and auditory neuropathy)

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