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SLX1A-SULT1A3 readthrough (non-protein coding) (SLX1A-SULT1A3)

Target
SLX1A-SULT1A3
Molecular classification
Other (non-coding RNA, readthrough transcript)
01

Overview

This locus encodes a readthrough RNA transcript that merges the SLX1A (structure-specific endonuclease subunit A) and SULT1A3 (sulfotransferase family 1A member 3) genes on chromosome 16[1][2][5]. The transcript is likely subject to nonsense-mediated mRNA decay (NMD) and does not produce a functional protein product[1][2][5]. Therefore, SLX1A-SULT1A3 itself is not a protein or drug target, though SULT1A3 as a separate gene encodes a legitimate drug-metabolizing enzyme.

Other names
HAST3M-PSTST1A3STMSULT1A3TL-PSTAryl sulfotransferase 1A3/1A4Catecholamine-sulfating phenol sulfotransferaseMonoamine-sulfating phenol sulfotransferasePlacental estrogen sulfotransferaseSulfotransferase 1A3Sulfotransferase 1A3/1A4Sulfotransferase, monoamine-preferringThermolabile phenol sulfotransferase

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