SLX1B-SULT1A4 readthrough (SLX1B-SULT1A4)

SLX1B-SULT1A4 readthrough is a naturally occurring chimeric transcript resulting from transcriptional read-through between the adjacent SLX1B and SULT1A4 genes on chromosome 16. It is recognized as a candidate for nonsense-mediated mRNA decay and is unlikely to result in production of a protein product or to possess a functional role. The constituent genes, SLX1B and SULT1A4, respectively encode an endonuclease subunit and a phenol-preferring sulfotransferase enzyme, but the read-through transcript itself is not considered a therapeutic target[1][2][4][8].

Other names

SLX1B-SULT1A4SLX1B-SULT1A4 readthroughSLX1 structure-specific endonuclease subunit homolog B–sulfotransferase family cytosolic 1A phenol-preferring member 4 readthrough

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