Small cysteine and glycine repeat-containing protein 3 (SCYGR3)

Small cysteine and glycine repeat-containing protein 3 (SCYGR3) is a member of the keratin-associated protein (KAP) family, which forms the matrix that cross-links with keratin intermediate filaments to provide structural integrity and mechanical properties to keratinized tissues such as hair, nails, and wool. KAPs, including SCYGR3, are not signal transduction molecules, receptors, enzymes, or transcription factors, but rather structural components with diverse and often family-member-specific functions. Expression and proper regulation of these proteins are essential for the normal development and maintenance of hair and related integumentary structures, affecting characteristics like fiber strength, resilience, and quality[2]. There is currently no evidence to support SCYGR3 as a therapeutic target or receptor, and it does not have a defined role in major human diseases.\n\nNo information was found linking SCYGR3 (KRTAP28-3) to classical drug targeting, biomarker use, or safety concerns. If you seek a typical receptor, enzyme, or transporter, this is not an appropriate target; it is best classified under structural/other protein categories within molecular family ontologies.

Other names

Small cysteine and glycine repeat containing 3SCYGR3Keratin-associated protein 28-3KRTAP28-3keratin associated protein 28-3