Target intelligence / Profile preview

Small cysteine and glycine repeat-containing protein 7 (SCYGR7)

Target
SCYGR7
Molecular classification
Other (keratin-associated protein, structural protein)
01

Overview

Small cysteine and glycine repeat-containing protein 7 (SCYGR7) is a member of the keratin-associated protein (KRTAP) family. It is a structural protein found in the hair cortex, where it embeds and cross-links with hair keratin intermediate filaments via disulfide bonds, contributing to formation of a rigid, resilient hair shaft. The matrix proteins in which SCYGR7 is found include high-sulfur and high-glycine-tyrosine keratins.

Other names
Small cysteine and glycine repeat-containing 7KRTAP28-7keratin-associated protein 28-7keratin associated protein 28-7SCGR7
02

Biological functions

Structural component of hairdisulfide cross-linking with hair keratins

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