Target intelligence / Profile preview

Small cysteine and glycine repeat-containing protein 9 (SCYGR9)

Target
SCYGR9
Molecular classification
Other (Keratin-associated protein pseudogene)
01

Overview

Small cysteine and glycine repeat-containing protein 9 (SCYGR9) is likely a member of the keratin-associated protein (KAP) family, which are structural proteins that associate with keratin intermediate filaments in hair and wool through disulfide bonds, conferring mechanical properties such as strength and rigidity. The “KRTAP28p1” designation and several aliases indicate that this gene is a pseudogene, meaning it probably does not encode a functional protein in humans. While other KAPs are involved in hair structure and potentially cytoskeletal functions, there is no evidence that SCYGR9 is therapeutically actionable, involved in disease, or interacts with drugs. The nomenclature is inconsistent and may reflect either misannotation or overlap with other keratin-associated pseudogenes. Key points of caution: - “SCYGR9” and its aliases reference a keratin-associated pseudogene, making it highly unlikely to be a therapeutic target. - The lack of standardized nomenclature and functional evidence raises the possibility of misidentification or incomplete annotation. If you are searching for an actionable therapeutic target or biomarker, SCYGR9 does not currently qualify based on any available evidence. For structured data applications, mark it as incorrect for target curation purposes.

Other names
SCYGR9KRTAP28p1KRTAP28-9Keratin-associated protein 28-1 pseudogeneKeratin associated protein 28 family pseudogene 1Keratin associated protein 28-9
02

Mechanism of action

None known

03

Biological functions

Other (putative, not established)Possibly structural association with hair/wool keratin via disulfide bonds
04

Disease associations

Other (not established; no links to cancer, inflammation or other diseases found for SCYGR9 specifically)

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