Target intelligence / Profile preview

Small integral membrane protein 8 (SMIM8)

Target
SMIM8
Molecular classification
Integral membrane protein, Single-pass or multi-pass membrane protein (specific topology not clearly established)
01

Overview

Small integral membrane protein 8 (SMIM8) is a protein found in several species, including mouse (Mus musculus) and human. It is 97 amino acids in length (mouse), and is predicted to be embedded within cellular membranes, classifying it as an integral membrane protein[3][6]. The function of SMIM8 is currently unknown; no specific role in signaling, transport, or enzymatic activity has been reported, nor is it currently a recognized therapeutic target. There is no known association with human diseases, drug interactions, or use as a biomarker. The protein’s classification is based strictly on its predicted membrane localization and sequence.

Other names
SMIM8Smim8 (in mouse)Small integral membrane protein 8
02

Mechanism of action

None described

03

Biological functions

Unknown; described as a component of cellular membranes, but no specific function has been established
04

Disease associations

None described; no current evidence linking SMIM8 to a specific disease in the literature

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