Small nucleolar RNA SNORD11 (SNORD11)

Small nucleolar RNA SNORD11 (SNORD11; LOC124900371; ENSG00000238819) is a non-coding RNA gene located on chromosome 15 (15:46,351,662-46,351,746, reverse strand, GRCh38)[1][5]. SNORD11 belongs to the C/D box class of snoRNAs, a group involved in the chemical modification of other RNA molecules, mainly 2'-O-methylation of ribosomal RNA. This gene does not encode a protein and is not recognized as a therapeutic target, receptor, enzyme, transporter, or similar pharmacological entity. Due to its classification as a snoRNA, its primary biological function is guiding the methylation of target RNAs in the nucleolus, essential for ribosome biogenesis and RNA stability. There is currently no evidence linking SNORD11 directly to disease mechanisms, drug interaction, or utility as a biomarker. Notes on structure and classification: SNORD11 is part of the C/D box family of small nucleolar RNAs, typically responsible for the site-specific 2'-O-methylation of substrate RNAs, mainly ribosomal RNA. It is not a receptor, transporter, or enzyme. As such, it is not generally considered a therapeutic target in the conventional sense used in drug development or pharmacology[1][5]. No interacting drugs or safety concerns have been reported in the literature or curated databases. Summary: SNORD11 is a C/D box class small nucleolar RNA involved in RNA modification, not a protein-coding gene, and is not considered a conventional drug target. No direct disease associations, drug interactions, or biomarkers are reported for this target at present[1][5].

Other names

SNORD11LOC124900371ENSG00000238819