Small nucleolar RNA SNORD56B (SNORD56B)

Small nucleolar RNA SNORD56B is a non-coding RNA belonging to the C/D box family of snoRNAs. It contains conserved sequence motifs called the C box (UGAUGA) and D box (CUGA) and directs site-specific 2'-O-methylation of substrate RNAs, primarily ribosomal RNA[1][5]. SNORD56B is encoded within an intronic region of a host gene (NOL5A), and, like other snoRNAs, is a constituent of snoRNP complexes together with proteins such as NOP56, NOP58, Snu13, and fibrillarin[3][5]. These complexes are essential for rRNA processing and assembly, localizing to the nucleolus for modification of nascent rRNAs[5]. While important for cellular homeostasis, SNORD56B itself is not identified as a direct therapeutic target, and it has not been associated with drug interactions or safety issues.

Other names

RNU56BRNA, U56B small nuclearSNORD56B

Not applicable—no approved drugs or drug candidates target SNORD56B for therapeutic intervention.