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Target intelligence / Profile preview
Small nucleolar RNA SNORD66 (SNORD66)
- Target
- SNORD66
- Molecular classification
- Small nucleolar RNA, C/D box snoRNA, Non-coding RNA
01
Overview
Small nucleolar RNA SNORD66 (also referred to as HBII-142 or LOC124900230) is a non-coding RNA belonging to the C/D box class of small nucleolar RNAs (snoRNAs). SNORD66 guides the 2'-O-methylation of specific sites in target RNAs, often rRNA or snRNA, which is important for the post-transcriptional modification and maturation of ribosomal RNA within the nucleolus. It is not a protein, receptor, or therapeutic target, but has been studied as a potential RNA biomarker in some cancer types. SNORD66 is not currently implicated as a direct therapeutic target, nor are there any known small molecule drugs or biologics targeting this RNA.
- Other names
- HBII-142SNORD66LOC124900230
02
Biological functions
RNA modification (2'-O-methylation of ribosomal RNA)RNA processing
03
Disease associations
Other (has been reported in some cancer biomarker studies, but not a recognized major disease gene or therapeutic target)
04
Biomarkers
Potential (experimental biomarker in some cancer studies, but not established clinically)
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