Small nucleolar RNA SNORD83 (SNORD83)

Small nucleolar RNA SNORD83 is a member of the C/D box snoRNA family, which are short, non-coding RNAs that guide sequence-specific 2′-O-ribose methylation of target RNAs—primarily ribosomal RNA—during ribosome biogenesis[2][3][4][5]. SNORD83 functions as a recognition scaffold inside nucleolar ribonucleoprotein complexes (snoRNPs), recruiting proteins such as fibrillarin, NOP56, NOP58, and SNU13 to catalyze methylation at specific sites in RNA[2][3][4][5]. It is highly conserved, localized to the nucleolus, and participates in the maturation and stabilization of ribosomes. SNORD83 is not a receptor, enzyme, or drug target, but its proper function is essential for cell viability and protein synthesis through its role in ribosomal RNA processing[2][4][5]. Direct associations with disease or use as a clinical biomarker are not described for SNORD83 as of current literature.

Other names

SNORD83LOC124903098Small nucleolar RNA, C/D box 83

Not applicable. No drugs currently target SNORD83.