Small nucleolar RNA U109 (snoU109)

Small nucleolar RNA U109 (abbreviated snoU109, also known as LOC124901856, ENSG00000238832) is a non-coding RNA gene found on chromosome 7q22.3 in humans. It does not encode a protein but is classified as a snoRNA, a type of small, stable RNA molecule that primarily functions in the chemical modification and processing of other RNA species, most commonly ribosomal RNAs. snoRNAs act as guide RNAs, recognizing target sites on ribosomal RNA and facilitating site-specific modifications, which are essential for proper ribosome biogenesis and function. There is no current evidence linking snoU109 directly to any disease role, drug interactions, or use as a clinical biomarker[1][4][7]. This gene is a non-coding RNA, specifically a snoRNA—not a protein, enzyme, receptor, transporter, or conventional therapeutic target. Based on available gene databases and gene nomenclature, ENSG00000238832 (LOC124901856) is considered an "uncharacterized" but known small nucleolar RNA[4][7]. Because it is not a protein-coding gene and does not have an established disease association, it is not considered a standard therapeutic or diagnostic target. Supporting evidence from GeneCards and NCBI classifies LOC124901856 as an "uncharacterized" non-coding gene and specifically as a pseudogene or snoRNA, not as a protein-encoding gene[4][7]. The Angiogenes database lists ENSG00000238832 as snoU109, classified as a snoRNA gene with 22 transcripts, confirming its molecular class and gene location[1]. ENSG00000238832 encodes a small nucleolar RNA (not a protein or receptor), is not considered a therapeutic target, and is involved in ribonucleic acid modification, with no known disease or drug associations[1][4][7]. No associated protein structure or mechanism, nor established therapeutic, diagnostic, or safety data are available.

Other names

LOC124901856snoU109