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Small nucleolar RNA U13 (SNORD13)

Target
SNORD13
Molecular classification
Small nucleolar RNA, Non-coding RNA, snoRNA
01

Overview

Small nucleolar RNA U13 (SNORD13) is a non-coding RNA gene that produces a small nucleolar RNA molecule involved in the chemical modification and processing of ribosomal RNA (rRNA) within the nucleolus. SNORD13 participates in the site-specific 2'-O-methylation of rRNA, a post-transcriptional modification important for proper ribosome biogenesis and function. It is not protein-coding and does not encode a polypeptide, receptor, or enzyme, and thus is not considered a direct therapeutic target. ENSG00000238764 is classified as "small nucleolar RNA U13" based on data from multiple gene and RNA resources. It maps to the class of small nucleolar RNAs (snoRNAs), which are non-coding RNAs that guide modification of other RNAs, especially rRNAs, in the nucleolus. It is distinct from protein-coding genes and is not in the molecular classes commonly considered druggable therapeutic targets (such as GPCRs, enzymes, or ion channels). Consequently, there are currently no known drugs, biomarkers, or established therapeutic mechanisms related to this target. No warnings regarding the validity of the sequence or annotation are associated with ENSG00000238764 in public gene/protein databases. Therefore: It is not a canonical therapeutic target (does not encode a protein or receptor). The name, sequence, and function are valid, but its application is currently restricted to basic RNA biology research. For all functional attributes (biological function, mechanism, disease role, drugs), there is no established therapeutic or biomarker use. ENSG00000238764 is properly annotated as small nucleolar RNA U13 (SNORD13), a non-coding RNA involved in rRNA modification, not a protein, and not a drug or biomarker target.

Other names
Small nucleolar RNA U13SNORD13LOC124905270
02

Biological functions

RNA modification (site-specific 2'-O-methylation of ribosomal RNA)Processing/modification of rRNA

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