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Small ribosomal subunit protein uS2 is a universally conserved component of the small ribosomal subunit, present in all domains of life. It plays a critical role in the assembly and function of the ribosome, which is responsible for translating mRNA into proteins. In eukaryotes, it is part of the 40S subunit; in prokaryotes, it is found within the 30S subunit. In vertebrates, post-translational modification (acetylation) converts monomeric uS2 into a dimeric form that functions as a cell surface laminin receptor.
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