SMC3 pseudogene 1 (SMC3P1)

SMC3 pseudogene 1 (SMC3P1) is a retrotransposed homologous pseudogene located at the 2q11.2 locus, likely derived from the final five exons of the SMC3 gene. While SMC3 encodes a critical subunit of the cohesin complex involved in vital cellular processes like sister chromatid cohesion, chromosome segregation, and DNA repair, SMC3P1 does not encode a functional protein and lacks known biological functions. As a non-functional genomic element resulting from retrotransposition, SMC3P1 typically lacks therapeutic relevance, is not considered a biological target, and has no known drug interactions or disease associations. The main molecule of interest for biological functions and disease roles (e.g., Cornelia de Lange syndrome) is SMC3, not SMC3P1. Misidentification or confusion between SMC3 and SMC3P1 is possible, but SMC3P1 is not a valid molecular target. Therefore, any query identifying SMC3 pseudogene 1 as a molecular target is incorrect, as it refers to a pseudogene and not a bona fide therapeutic target.

Other names

SMC3P1